sleep effects the chemistry of the body so a dramatic shift in sleep pattern will produce the effect you describe. And those changes should help you survive the day. I'm miserable. I havent slept in 4-5 days, and by that I don't mean poor sleep, I mean I have NOT slept at all for 4 days. Been there myself many times... As for the 'dire consequences' of a lack of sleep, as a medical layman I say to you: don't worry about it excessively. X Research source With a little bit of preparation and a regular schedule, you'll be able to stay awake and push through to the end. Exercise will also help you sleep better at night. With multiple deployments under his belt, Kelley has had many instances of ⦠Also you will be hungry. No big deal. I slept but only about 15-20 minutes a day of real sleep. My body is ready for bed, but my brain is not. I have been taking Melatonin or Lorazepam and neither seems to work for me. Lots of coffee, loud music, brisk walks, and utter desperation. Seriously, though, welcome to the world of quite a few professions during their university years. Some people said I looked like death others just did a double take stare like they saw a zombie. After the first night, I couldnât sleep. Is this still a problem ?! If you have been able to sleep well before, the first thing to do is to figure out what may recently have changed. I'm not really anxious or stressed. At this point the muscle fatigue is really bad to the point that even sitting up is just... heavy. It feels normal, then gets bad, then normal again like nothing happened and in the end it's heavenly, let me walk you through it. ⦠after a few years you graduate with a degree in medicine. Donât binge eat after. I haven't slept in about 48 hours. I don't know what to do. For the first 17-18 hours, you don't really feel much except a little routine tiredness. It got harder and harder to stay awake, By day three I started hallucinating. I tried switching on the TV, hoping I'd get sleepy and just doze off. I once stayed up for four days in grad school to finish some projects. I'm tired, but I just cannot get to sleep. So I actually have recent experience with this. I've tried laying down and going to sleep, but its like trying to go to bed when you're totally wide awake. This may give you a clue as to the reason for your insomnia: * New supplements, medications, foods, beverages? Lasted about 3-4 weeks. You probably will lose some mental and physiological defense systems. I've layed in bed for hours. Scott Kelley, a 10-year Army veteran, knows about sleep deprivation. Science says this is actually a good thing to do occasionally. TLDR: Not a whole heck of a lot that you can tell. Although you should avoid going longer than 3-4 days without sleep, you can safely stay up for a few days as long as you plan to get full nights of sleep for 1-2 days afterwards. I like the answers you received and just have one question. 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